Program October 8

09:00 Conjugates for targeted delivery
(Chairs: Henry Herce, Tom Grossmann)
09:00 Dario Neri
Armed antibodies for the treatment of cancer and of chronic inflammation: from the bench to the clinic
09:30 Jean Philippe Pellois
Protein delivery into live cells by simple co-incubation with an endosomolytic agent
10:00 Timo D. Müller
Targeted delivery of nuclear hormones for the treatment of the metabolic syndrome
10:20 David Margulies
Using Synthetic Molecules to Communicate with Proteins and Make Them Talk to Each Other
10:40 Hidde Ploegh
Sortase-based strategies to engineer antibody fragments
11:10 Coffee Break
11:40 Rising Stars in Chemical Biology
(Chair: Haian Fu)
11:40 Alessio Ciulli
Achieving intra-BET selectivity of BET bromodomain chemical probes: bump-and hole and PROTAC approaches
12:00 Evan Miller
Electrophysiology, Unplugged: New Small Molecule Fluorophores for Optical Interrogation of Neuronal Voltage
12:20 Edward A. Lemke
Genetically encoded chemical precision tools to study protein plasticity at single molecule and super-resolution
12:40 Keynote by Carolyn Bertozzi
Bioorthogonal chemistries for engineering protein in cells
(Chair: Christian Hackenberger)
13:25 Lunch
In parallel Poster Session II
Topics: Cheminformatics & Chemical Systems Biology, Molecular Imaging, Probing the structure and function of PTMs
14:30 Antiinfectives
(Chairs: Mikael Elofsson, Jonathan Baell)
14:30 Rolf Müller
Innovative antibiotics from microorganisms: Two case studies
15:00 Michael P. Manns
Direct acting antiviral agents (DAAs) against hepatitis C
15:30 Lixin Zhang
A Novel Antibiotic Drug Screening Platform Targeting Pathogen-Host Interactions
15:50 Rainer Haag
Multivalent 1D-, 2D and 3D-Glycopolymers as Antiviral Drug Candidates
16:10 Maria Maneiro
Irreversible Inhibition of Type I Dehydroquinase for Antivirulence Drug Discovery
16:30 Coffee Break
17:00 Speed Talks on Posters
Held by invited poster presenters
(Chairs: Annika Jenmalm Jensen, Phil Gribbon)
18:00 Wine & Cheese
In parallel Poster Session II
Topics: Cheminformatics & Chemical Systems Biology, Molecular Imaging, Probing the structure and function of PTMs
20:00 Conference Dinner